Tumor suppressor genes Notes: Definitions & Explanations PDF | Download eBooks
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Tumor suppressor genes Definition:
Cells contain genes whose normal products inhibit cell division, such genes are called tumor-suppressor genes because the proteins they encode help prevent uncontrolled cell growth.
Campbell Biology by J.B. Reece, L.A. Urry, M.L. Cain, S.A. Wasserman, P.V. Minorsky, R.B. Jackson
Tumor suppressor genes Notes:
A tumor suppressor gene, which is also called an antioncogene, is a gene that protects a cell from becoming cancerous. When this gene mutates to cause a loss or reduction in its function, the cell can progress to cancer, and this usually happens in combination with other genetic changes. Common examples of tumor suppressor genes include caretaker genes and gatekeeper genes which have important function in regulating the cell cycle and growth.
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