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Study Allele Specific RNAi lecture notes PDF with molecular biology definitions and explanation to study What is Allele-Specific RNAi?. Study allele specific rnai explanation with molecular biology terms to review molecular biology course for online degree programs.

Allele Specific RNAi Definition:

  • Introduction of an altered copy of a gene whose mRNA will not be destroyed by RNAi targeted to the endogenous copy of the gene..

    Molecular Biology by Robert F. Weaver



Allele Specific RNAi Notes:

RNAi (RNA interference) or sequence-specific posttranscriptional gene silencing, is induced by small double stranded RNAs, called small interfering RNA strands (siRNA). These siRNA duplexes have the ability of inhibiting the expression of a specific allele, without interfering with the expression of other alleles. This is called allele-specific silencing or RNAi.

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