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Study Apurinic Site (AP Site) lecture notes PDF with molecular biology definitions and explanation to study What is Apurinic Site (AP Site)?. Study apurinic site (ap site) explanation with molecular biology terms to review molecular biology course for online degree programs.

Apurinic Site (AP Site) Definition:

  • A deoxyribose in a DNA strand that has lost its purine base..

    Molecular Biology by Robert F. Weaver



Apurinic Site (AP Site) Notes:

Apurinic Site (AP Site) is the location on a DNA strand (or in RNA sometimes), that does not carry a purine base. In other words the purine bases from the strand are lost either spontaneously or due to some damage. It is estimated that on a daily basis, about 10,000 apurinic sites can be generated in a cell under physiological conditions.

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