Catabolite Activator Protein (CAP) Notes: Definitions & Explanations PDF | Download eBooks
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Catabolite Activator Protein (CAP) Definition:
A protein that regulates the expression of genes encoding catabolite repressible enzymes; also called cyclic AMP receptor protein (CRP).
Prescott's Microbiology 9th Edition by Joanne Willey, Linda Sherwood, Christopher J. Woolverton
Catabolite Activator Protein (CAP) Notes:
Catabolite activator proteins are trans-acting transcriptional activators, which are present in the form of homodimers in solutions. CAP's each subunit is made of a DNA-binding domain at the C-terminus and a ligand-binding domain at N-terminus. Two molecules of cAMP bind dimeric CAP with negative cooperativity.
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