Pathogen associated molecular patterns (PAMPs) Notes: Definitions & Explanations PDF | Download eBooks
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Pathogen associated molecular patterns (PAMPs) Definition:
Pathogen-associated molecular patterns (PAMPs; formerly called elicitors), molecular sequences that are specific to certain pathogens.
Campbell Biology by J.B. Reece, L.A. Urry, M.L. Cain, S.A. Wasserman, P.V. Minorsky, R.B. Jackson
Pathogen associated molecular patterns (PAMPs) Notes:
These molecules can be referred to as small molecular motifs conserved within a class of microbes. They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. A vast array of different types of molecules can serve as PAMPs, including glycans and glycoconjugates. PAMPs activate innate immune responses, protecting the host from infection, by identifying some conserved nonself molecules. Bacterial lipopolysaccharides (LPSs), endotoxins found on the cell membranes of gram-negative bacteria, are considered to be the prototypical class of PAMPs. LPSs are specifically recognized by TLR4, a recognition receptor of the innate immune system.
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